TNF-α and IL-1 β Cytokine Gene Polymorphism in Patients with Nasal Polyposis
نویسندگان
چکیده
منابع مشابه
TNF-α and IL-1 β Cytokine Gene Polymorphism in Patients with Nasal Polyposis.
Objective Nasal Polyp (NP) is a benign mass of the paranasal sinuses that protrudes into the nasal cavity. The exact underlying pathogenesis is not known. In this study we aimed to determine the genetic susceptibility of NP formation in relation to TNF-α-308 and IL-1β-511 promoter region gene polymorphisms. Methods A total of 71 patients with NP with asthma (n=21) or without asthma (n=50) wer...
متن کاملTNF-α, TNF-β and IL-10 gene polymorphism and association with oral lichen planus risk in Saudi patients
OBJECTIVES Oral lichen planus (OLP) is a chronic inflammatory oral mucosal disease. Cytokines play an important role in the pathogenesis and disease progression of OLP. Various reports have implicated cytokine gene polymorphisms in susceptibility to develop some immune mediated conditions including OLP. The purpose of this study was to investigate the association of tumor necrosis factor (TNF)-...
متن کاملTNF-α, TNF-β, IL-6, and IL-10 Polymorphisms in Patients with Lung Cancer
Apart from cigarette smoking, genetic factors seem to be of importance in the development of lung cancer. The present case-control study investigated frequencies of five inflammatory response gene polymorphisms (TNF-alpha-308, TNF-beta-Intron1-252, IL-6-174, IL-10-819 and IL-10-1082) in patients with lung cancer and controls. The study population consisted of 117 patients with lung cancer (77 p...
متن کاملTNF-α and TNF-β Gene Polymorphism in Saudi Rheumatoid Arthritis Patients
BACKGROUND Tumor necrosis factor (TNF)-α and -β are cytokines with a wide range of inflammatory, apoptotic and immunomodulatory activities. TNF-α promoter -308 G < A polymorphism has been reported to be associated with rheumatoid arthritis (RA) with inconsistent results. OBJECTIVE The aim of this study is to elucidate a possible association of TNF-α (G-308A) and TNF-β (A+252G) polymorphisms w...
متن کاملSalivary VEGF-R3, TNF-α, TGF-β and IL-17A/F Levels in Patients with Minor Aphthous
Background : Recurrent aphthous stomatitis (RAS) is one of the most common mucosal ulcerative of oral cavity. Role of immune system, especially cytokines in immunopathogenesis of aphthous stomatitis was not highly considered. The aim of this study was to evaluate the levels of salivary cytokines, including VEGF-R3, TGF-&beta1, TNF-&alpha, and IL-17A/F in patients with RAS in two clinical stages...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Turk Otolarengoloji Arsivi/Turkish Archives of Otolaryngology
سال: 2017
ISSN: 0304-4793,0304-4793
DOI: 10.5152/tao.2017.2389